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Albert Bolshakov
Albert Bolshakov

Sex With Mature Man



Among patients with systemic lupus erythematosus (SLE), cancer risks overall were associated with older age at diagnosis and male sex, and lung cancer specifically was related to smoking, analysis of data from a large multicenter cohort found.




sex with mature man



In a multivariable analysis, the hazard ratio for any type of cancer among patients enrolled in the Systemic Lupus International Collaborating Clinics Inception Cohort was 1.05 (95% CI 1.03-1.06) for greater age at baseline, while the risk for women was lower, with a hazard ratio of 0.47 (95% CI 0.26-0.85), reported Sasha Bernatsky, MD, of McGill University in Montreal, and colleagues.


As shown in their study online in Arthritis Care & Research, for lung cancer specifically a history of smoking more than 15 cigarettes per day was associated with an almost seven-fold increased risk (HR 6.64, 95% CI 1.43-30.9).


Interest has been growing with regard to the risk of cancer among patients with autoimmune diseases, including lupus, because of a potential role of inflammation in malignancy development. In addition, certain medications, such as cyclophosphamide, have been linked with cancer in the past.


To address this knowledge gap, the researchers analyzed data for 1,668 patients enrolled in the cohort from 1999 to 2011, who were seen yearly with information collected on disease activity, medication usage, and cancer diagnoses.


When the researchers compared the incident cancers according to baseline patient characteristics, the results showed that whereas 89.3% of patients without cancer were women, only 78.3% of those who developed cancer were.


Mean age at the time of SLE diagnosis was 34.2 in the no-cancer group compared with 45.6 in the cancer group. Current or past smoking was reported in 33.3% of the no-cancer group but in 47.7% of the cancer group. White race was reported for 48.7% of the no-cancer group vs 67.7% of the cancer group.


In an unadjusted univariate analysis, factors positively associated with any type of cancer were older age at SLE diagnosis (HR 1.06, 95% CI 1.04-1.07), white race (HR 2.24, 95% CI 1.33-3.78), and ever smoking (HR 1.72, 95% CI 1.06-2.80), while female sex was associated with a lower risk (HR 0.35, 95% CI 0.20-0.60). However, in the multivariate analysis, only older age and female sex remained significant.


The researchers then estimated risks for the specific types of cancer. For breast cancer, only older age at the time of diagnosis showed a significantly increased risk in the multivariate analysis (HR 1.06, 95% CI 1.02-1.10), while antimalarial use was associated with a lower risk (HR 0.28, 95% CI 0.09-0.90).


None of the lung cancer patients had been treated with cyclophosphamide or methotrexate, but all had received long-term treatment with antimalarials; it was not possible, therefore, to provide risk estimates for those medications, the team noted.


With hematologic cancers, once again older age at SLE diagnosis had a significant association (HR 1.06, 95% CI 1-1.13), as did having ever been in the highest quartile of SLE disease activity (HR 7.14, 95% CI 1.13-45.3). All patients with these malignancies were white and had ever smoked but none had been treated with cyclophosphamide, so risk estimates for those factors also could not be calculated.


The observation that male sex and older age at the time of SLE diagnosis were associated with higher risks in most types of cancer "may be, at least in part, because these demographic groups are at greater cancer risk in the general population," Bernatsky and colleagues wrote.


Aging brings life transitions that can create opportunities for older adults to redefine what sexuality and intimacy mean to them. Some older adults strive for both a sexual and intimate relationship, some are content with one without the other, and still others may choose to avoid these types of connections.


With age, impotence (also called erectile dysfunction, or ED) also becomes more common. ED is the loss of ability to have and keep an erection, and the erection may not be as firm or as large as it used to be. ED is not a problem if it happens every now and then, but if it occurs often, talk with your doctor.


Chronic pain. Pain can interfere with intimacy. It can also cause tiredness and exhaustion, leaving little energy or interest in sex. Chronic pain does not have to be part of growing older and can often be treated. But, some pain medicines have effects on sexual function. Always talk with your health care provider if you have side effects from any medication.


Dementia. People with some forms of dementia may show an increased interest in sex and physical closeness, but they may not be able to judge what is appropriate sexual behavior. People with severe dementia may not recognize their spouse or partner but may still desire sexual contact. They may sometimes even seek this with someone else. It can be confusing and difficult to know how to handle this situation. Talking with a doctor, nurse, or social worker with training in dementia care may be helpful.


Incontinence. Loss of bladder control or leaking of urine is more common as people grow older. Extra pressure on the belly during sex can cause urine to leak. This can be helped by changing positions or by emptying the bladder before and after sex. The good news is that incontinence may be treated with medical treatments, bladder control training, and behavioral and lifestyle changes.


Stroke. The ability to have sex is sometimes affected by a stroke. A change in positions or medical devices may help people with ongoing weakness or paralysis to have sex. Some people with paralysis from the waist down are still able to experience orgasm and pleasure.


Surgery. Any kind of surgery can cause worry, and this can be even more troubling when the breasts or genital areas are involved, such as with the surgeries listed below. Most people are able to return to the kind of sex life they enjoyed before surgery. For some, these types of surgeries may even help them to increase their sex life options.


Talk with your health care provider about ways to protect yourself from STDs and infections during your regular check-ups and if you have any concerns between visits. Remember, you are never too old to be at risk.


Researchers are partnering with people in SGM communities to learn more about the health disparities and other factors affecting these groups. For example, the Aging with Pride: National Health, Aging, Sexuality and Gender Study, funded in part by NIA, is a long-term effort involving more than 2,000 older adults to better understand the aging, health, and well-being of SGM populations and their families.


If ED is the problem, it can often be managed with medications or other treatments. A health care professional may suggest lifestyle changes, such as limiting alcohol or increasing physical activity, to help reduce ED. A health care professional may also prescribe testosterone for people with low levels of this hormone. Although taking testosterone may help with ED, it may also lead to serious side effects and can affect how other medicines work. Make sure to talk with your health care provider about testosterone therapy and testing your testosterone levels. Be wary of any dietary or herbal supplements promising to treat ED. These products may have dangerous side effects or interact with prescription medicines. Always talk to a health care provider before taking any herb or supplement. Another important reason to see your health care provider for ED is that it may be a sign of an underlying health problem that should be treated, such as clogged blood vessels or nerve damage from diabetes.


You might be worried about these changes. But remember, they don't have to end your enjoyment of sex. Working with your changing body can help you keep a healthy and happy sex life. For instance, you may need to change your sexual routine to include more stimulation to become aroused.


For example, if you're worried about having sex after a heart attack, talk with your health care provider about your concerns. If arthritis pain is a problem, try different sexual positions. Or try using heat to lessen joint pain before or after sexual activity.


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Can you see why that would be attractive to a 30-year-old woman looking to start a family of her own? She has a choice, date a younger guy who doesn't know his butt from his elbow when it comes to DIY or date an experienced man who knows how to fix her problems without the help of his parents.


Once again, proceed with caution. Laughter does not equate to lust and isn't a sign she's ready to jump in the sack with you. However, it does show that she finds you endearing and a joy to be around.


Again, this does not mean she's guaranteed to be romantically obsessed with you. However, it's a great sign that she's comfortable around you and feels that she's on a level with you where she can get physical.


You'll know things are serious when all of her friends know about you. If you're getting friendly with a younger woman and all of a sudden her friends seem to know a lot about you, chances are you're in luck and can start to consider taking things to the next level.


However, you need to consider whether you're still in that place. As an older guy, you may have already built your business or reached your professional goals. Now might be the time that you want to relax and reap the benefits of your hard work with the lady in your life. 041b061a72


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